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Technical Inside the SQL Server Query Optimizer
"Multiplexed Networks for Embedded Systems: CAN, LIN, Flexray, Safe-by-Wire..." by Dominique Paret (Repost)
Dino Esposito, "Building Web Solutions with ASP.Net and ADO.NET" (Repost)
Learning Core Audio: A Hands-On Guide to Audio Programming for Mac and iOS
Power Performance - Multimedia Storytelling for Journalism and Public Relations
pluralsight-training.net SQL Server: Transact-SQL Basic Data Retrieval [2012, ENG]
pluralsight-training.net SQL Server: Collecting and Analyzing Trace Data [2012, ENG]
Pluralsight.net - Introduction to Nancy-JWARE
Technical Structured Programming with C++
Technical Getting Started with LaTeX by David R. Wilkins
Windows A Third Window - Natural Life beyond Newton and Darwin
PLURALSIGHT.NET WINDOWS 8 METRO CONNECTED APPS-JGTiSO
PLURALSIGHT.NET WINDOWS 8 METRO APPLICATION DATA-JGTiSO
PLURALSIGHT.NET BUILDING WINDOWS 8 METRO APPS WITH C PLUS PLUS AND XAML-JGTiSO
PLURALSIGHT.NET BUILDING WINDOWS 8 METRO APPS WITH C SHARP AND XAML-JGTiSO
PLURALSIGHT.NET INTRODUCTION TO BUILDING WINDOWS 8 METRO APPLICATIONS-JGTiSO
Multimedia over IP and Wireless Networks - Compression, Networking, and Systems
Interactive Distributed Multimedia Systems and Telecommunication Services
The Art of Hardware Architecture - Design Methods and Techniques for Digital Circuits
Pro/ENGINEER WILDFIRE 5.0 Tutorial and MultiMedia CD
"Multiplexed Networks for Embedded Systems: CAN, LIN, Flexray, Safe-by-Wire..." by Dominique Paret (Repost)
Dino Esposito, "Building Web Solutions with ASP.Net and ADO.NET" (Repost)
Learning Core Audio: A Hands-On Guide to Audio Programming for Mac and iOS
Power Performance - Multimedia Storytelling for Journalism and Public Relations
pluralsight-training.net SQL Server: Transact-SQL Basic Data Retrieval [2012, ENG]
pluralsight-training.net SQL Server: Collecting and Analyzing Trace Data [2012, ENG]
Pluralsight.net - Introduction to Nancy-JWARE
Technical Structured Programming with C++
Technical Getting Started with LaTeX by David R. Wilkins
Windows A Third Window - Natural Life beyond Newton and Darwin
PLURALSIGHT.NET WINDOWS 8 METRO CONNECTED APPS-JGTiSO
PLURALSIGHT.NET WINDOWS 8 METRO APPLICATION DATA-JGTiSO
PLURALSIGHT.NET BUILDING WINDOWS 8 METRO APPS WITH C PLUS PLUS AND XAML-JGTiSO
PLURALSIGHT.NET BUILDING WINDOWS 8 METRO APPS WITH C SHARP AND XAML-JGTiSO
PLURALSIGHT.NET INTRODUCTION TO BUILDING WINDOWS 8 METRO APPLICATIONS-JGTiSO
Multimedia over IP and Wireless Networks - Compression, Networking, and Systems
Interactive Distributed Multimedia Systems and Telecommunication Services
The Art of Hardware Architecture - Design Methods and Techniques for Digital Circuits
Pro/ENGINEER WILDFIRE 5.0 Tutorial and MultiMedia CD
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Technical Genome Stability and Human Diseases (repost)
Posted on 2010-07-31
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More Heinz Peter Nasheuer, "Genome Stability and Human Diseases" Since the establishment of the DNA structure researchers have been highly interested in the molecular basis of the inheritance of genes and of genetic disorders. Scientific investigations of the last two decades have shown that, in addition to oncogenic viruses and signalling pathways alterations, genomic instability is important in the development of cancer. This view is supported by the findings that aneuploidy, which results from chromosome instability, is one of the hallmarks of cancer cells. Chromosomal instability also underpins our fundamental principles of understanding tumourigenesis: It thought that cancer arises from the sequential acquisition of genetic alterations in specific genes. In this hypothesis, these rare genetic events represent rate-limiting ‘bottlenecks’ in the clonal evolution of a cancer, and pre-cancerous cells can evolve into neoplastic cells through the acquisition of somatic mutations. This book is written by international leading scientists in the field of genome stability. Chapters are devoted to genome stability and anti-cancer drug targets, histone modifications, chromatin factors, DNA repair, apoptosis and many other key areas of research. The chapters give insights into the newest development of the genome stability and human diseases and bring the current understanding of the mechanisms leading to chromosome instability and their potential for clinical impact to the reader. Download
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