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Science/Engineering Foreign DNA in Mammalian Systems

Posted on 2010-03-16




Name:Science/Engineering Foreign DNA in Mammalian Systems
ASIN/ISBN:3527300899
Language:English
File size:9.8 Mb
Publisher: Wiley-VCH
ISBN: 3527300899
Publish Date: edition 2000
File Type: PDF
Pages: 194 pages
File Size: 9,8 mb
   Science/Engineering Foreign DNA in Mammalian Systems

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Foreign DNA in Mammalian Systems By Walter Doerfler

It is unlikely that the established genomes of present day organisms remain stable forever. It is conceivable that foreign DNA can gain entry into individual cells of an organism.

Foreign DNA is defined as genetic material that derives from another organism of the same or a different species. The natural environment is heavily "contaminated" with such foreign DNA, and mammals, like other organisms, are frequently exposed to foreign DNA in their environment, notably by ingesting their daily food supply. By necessity, the gastrointestinal tract also of all mammalian organisms is constantly in contact with foreign DNA. So far, next to nothing is known about defense mechanisms in mammals against the intrusion of foreign DNA. At least in cells growing in culture, the uptake and genomic fixation by integration of foreign DNA can readily be demonstrated.

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