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Fields Virology. 2 Volume Set (with CD-ROM) by Bernard N. Fields

In the early 1980s, Bernie Fields originated the idea of a virology reference textbook that combined the molecular aspects of viral replication with the medical features of viral infections. This broad view of virology reflected Bernie's own research, which applied molecular and genetic analyses to the study of viral pathogenesis, providing an important part of the foundation for the field of molecular pathogenesis. Bernie led the publication of the first three editions of Virology. Unfortunately, we lost Bernie to pancreatic cancer soon after the third edition went into production. The third edition became Fields Virology in his memory, and it is entirely fitting that the fourth edition continues to carry his name.

We have retained the general organization of the first three editions for the fourth edition. Part I contains chapters on general aspects of virology, and Part II contains chapters on replication and medical aspects of specific virus families and specific viruses of medical importance. In Part I, we have added new chapters on principles of virology, virus entry and uncoating, replication strategies of RNA viruses and DNA viruses, virus assembly, and virus vectors to enhance the utility of this book as well as that of Fundamental Virology as textbooks. In Part II we have added new chapters on the arteriviruses, the Bornaviridae, and Kaposi's sarcoma-associated herpes virus. We have also expanded the retrovirus section to include chapters on the nonhuman lentiviruses as well as human and primate viruses other than the lentiviruses and the lymphotropic retroviruses. The main emphasis continues to be on viruses of medical importance and interest, but other viruses are described in specific cases where more is known about their mechanisms of replication or pathogenesis. Although not formally a virus, prions are still included in this edition for historical reasons and because of the intense interest in the infectious spongiform encephalopathies.

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