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Science/Engineering DNA Repair Protocols (Methods in Molecular Biology) by Daryl S. Henderson

Posted on 2010-03-16




Name:Science/Engineering DNA Repair Protocols (Methods in Molecular Biology) by Daryl S. Henderson
ASIN/ISBN:1588295133
Language:English
File size:3.6 Mb
Publisher: Humana Press
Publish Date: 2nd edition (October 1, 2005)
ISBN: 1588295133
Pages: 512
File Type: PDF
File Size: 3.6 MB
   Science/Engineering DNA Repair Protocols (Methods in Molecular Biology) by Daryl S. Henderson

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DNA Repair Protocols (Methods in Molecular Biology) by Daryl S. Henderson

This collection of readily reproducible techniques for repairing mammalian DNA contains fourteen entirely new chapters and many extensively revised chapters. The methods presented cover cytogenetic analysis, measuring the cellular response to ionizing radiation, detecting single-strand (nicks) and double-strand DNA breaks, detecting the presence of "adducted" bases in DNA, and preparing mismatch repair (MMR) plasmid substrates. Among the highlights are excellent coverage of both base excision repair (BER) and nucleotide excision repair (NER), useful assays for identifying and quantifying UV-induced DNA lesions and DNA breakage, gene therapy, environmental mutagenesis and cancer, and gene targeting.

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