Dennis A. Smith, et al, "Pharmacokinetics and Metabolism in Drug Design (3527301976)

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The medical benefits of a drug are not only dependent on its biological effect, but also on its "life cycle" within the organism - from its absorption into the blood, distribution to tissue until its eventual breakdown or excretion by the liver and kidneys. Here, the authors, all of them employed at Pfizer in the discovery and development of new active substances, discuss the significant parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. The authors cover everything from the fundamental principles left up to the latest developments using high throughput methods to analyze the pharmacokinetic properties of active substances. Particular emphasis is placed on the impact of pharmacokinetic parameters on the discovery of new drugs - one of the most challenging tasks in global pharmaceutical research. Thus, this book is aimed at all those dealing professionally with the development and application of pharmaceutical substances. Furthermore, the readily comprehensible style of writing makes it equally suitable for students of pharmacy and related subjects, who feel that pharmacokinetics is covered too briefly in the standard textbooks.

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	Mass Spectrometry in Drug Metabolism and Pharmacokinetics Ragu Ramanathan "Mass Spectrometry in Drug Metabolism and Pharmacokinetics" Wiley \| 2008-12-31 \| ISBN: 0471751588 \| 390 pages \| PDF \| 9,8 MB This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studie ...
	Science/Engineering Drug Metabolism in Drug Design and Development Drug Metabolism in Drug Design and Development Publisher: Wiley-Interscience \| ISBN: 047173313X \| edition 2007 \| PDF \| 609 pages \| 4 mbDrug Metabolism in Drug Design and Development provides a practical description of what happens during t ...
	Science/Engineering Pharmacokinetics and Metabolism in Drug Design (Methods and Principles in Medicinal Chemistry) Pharmacokinetics and Metabolism in Drug Design (Methods and Principles in Medicinal Chemistry)Wiley-VCH \| ISBN: 3527313680 \| 2006-05-01 \| PDF \| 207 pages \| 1 Mb In this new edition of a bestseller, all the contents have been updated and new ...
	Evaluation of Drug Candidates for Preclinical Development: Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology Evaluation of Drug Candidates for Preclinical Development: Pharmacokinetics, Metabolism, Pharmaceutics, and ToxicologyPublisher: Wiley \| ISBN: 0470044918 \| edition 2010 \| PDF \| 289 pages \| 1,4 mb Emphasizes the integration of major areas ...
	EBook Torrents Pharmacokinetics And Metabolism In Drug Design-(Ebook-Pdf) - Che
	Science/Engineering Pharmacokinetics and Metabolism in Drug Design Dennis A. Smith, "Pharmacokinetics and Metabolism in Drug Design"Uploading My AH blog!!!! No mirrors please (Except RS) !!!

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