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Cytokines and Chemokines in Autoimmune Disease
Posted on 2010-04-14
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More Pere Santamaria (Editor), «» This volume is ideal for individuals interested in taking an in-depth look at how cytokines and chemokines participate in autoimmune disorders, and how cytokines and chemokines can be used as targets for therapeutic intervention. The outstanding features of this book are that it is divided in chapters each focusing on specific, highly prevalent autoimmune disorders. The role of cytokines and chemokines in each of these disorders is dissected in the context of the autoinimune responses that drive these diseases. Importantly, each chapter is meant to provide an in-depth review of how cytokines and chemokines participate in each disease, rather than very specific aspects of cytokine or chemokine biology. The book therefore provides an integrated view of how multiple cytokines and chemokines participate in the initiation and evolution of both systemic and organ-specific pathological immune responses. Table of contents: Autoimmune diseases and cytokines: pathogenesis and therapy. Pere Santamaria Cytokines, chemokines, their receptors and their genes: an overview. David J. Kelvin Cytokine and cytokine receptor genes in the genetic susceptibility and resistance to autoimmunity. Roland S. Liblau Cytokines, lymphocyte homeostasis and self-tolerance. Yiguang Chen Cytokines as effector mechanisms of tissue destruction in autoimmunity. Thomas W.H. Kay Cytokines in the pathogenesis and treatment of experimental autoimmune encephalomyelitis and multiple sclerosis. David O. Willenborg Chemokines in experimental autoimmune encephalomyelitis and multiple sclerosis. Trevor Owens Cytokines in the pathogenesis of pancreatic islet graft desruction in autoimmune diabetes. Alex Rabinovitch Chemokines and cytokines in autoimmune diabetes. Terry L. Delovitch Cytokines in the pathogenesis of rheumatoid arthritis and collagen-induced arthritis. Erik Lubberts Chemokines in rheumatoid arthritis N. Karin Cytokines and chemokines in virus-induced autoimmunity. Matthias G. Von Herrath Cytokines in the treatment and prevention of autoimmune responses. Terry B. Strom Cytokines and chemokines in human autoimmune skin disorders (SLE, pemphigus vulgaris). Thomas Schwarz Cytokines and chemokines in SLE. Frederick A. Houssiau
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