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Science/Engineering Cytogenetics, FISH and molecular testing in hematologic malignancies

Posted on 2010-03-15




Name:Science/Engineering Cytogenetics, FISH and molecular testing in hematologic malignancies
ASIN/ISBN:0415420091
Language:English
File size:12 Mb
Publish Date: 2008-01-28
ISBN: 0415420091
Pages: 319 pages
File Type: PDF
File Size: 12 MB
Other Info: Informa HealthCare
   Science/Engineering Cytogenetics, FISH and molecular testing in hematologic malignancies

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Wojciech Gorczyca, "Cytogenetics, FISH and molecular testing in hematologic malignancies"

Cytogenetics, fluorescence in situ hybridization (FISH) and molecular tests, especially polymerase chain reaction (PCR), play an important role in the management of patients with hematologic malignancies by helping to establish the diagnosis, as well as predict prognosis, response to treatment and disease progression. Chromosomal and molecular abnormalities provide the most reliable criteria for classification of hematopoietic tumors and often comprise the basis for targeted therapy. Cytogenetics, FISH and Molecular Testing in Hematologic Malignancies, provides a review of chromosomal and molecular changes in hematologic malignancies and correlates the karyotypic and genetic abnormalities with morphology, immunophenotype and clinical data. With over 180 figures and diagnostic algorithms, this text is essential reading for all pathologists, hematopathologists, hematologic oncologists, cytogenetists, cytogenetic technologists and cell biologists.

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