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Current Concepts in Normal and Abnormal Puberty,an Issue of Current Problems in Pediatric and Adoles

Posted on 2010-04-20




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cent Health Care

Current Concepts in Normal and Abnormal Puberty,

Current Problems in Pediatric and Adolescent Health Care

Volume 37, Issue 2,FEB 2007

Todd D. Nebesio, MD, and Erica A. Eugster, MD

Secular Trends and the Timing of Puberty 50

Variants of Precocious Puberty 51

Premature Thelarche 51

Premature Adrenarche 52

Pathologic Precocious Puberty 52

Central Precocious Puberty-Etiologies 53

Central Precocious Puberty-Treatment 53

Peripheral Precocious Puberty-Etiologies 55

Congenital Adrenal Hyperplasia 55

McCune-Albright Syndrome 55

Familial Male-Limited Precocious Puberty 56

Pseudoprecocious Puberty (Van Wyk-Grumbach

Syndrome)57

Endocrine Disruptors 57

Tumors 58

Other Disorders 58

Prepubertal Gynecomastia 58

Pubic Hair of Infancy 60

Premature Menses 60

Delayed Puberty 60

Constitutional Delay of Growth and Puberty 61

Hypothalamic-Pituitary Dysfunction 61

Primary Hypogonadism 62

Gynecomastia 64

Delayed Puberty-Treatment 65

Conclusion 66

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