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Science/Engineering Creatine and Creatine Kinase in Health and Disease (2007)

Posted on 2010-03-15




Name:Science/Engineering Creatine and Creatine Kinase in Health and Disease (2007)
ASIN/ISBN:1402064853
Language:English
File size:2.8 Mb
Publisher: Springer
Language: English
ISBN: 1402064853
Pages: 450 pages
Publish Date: 2007
File Type: PDF
File Size: 2.8 Mb
   Science/Engineering Creatine and Creatine Kinase in Health and Disease (2007)

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Creatine and Creatine Kinase in Health and Disease

Description: Although creatine was discovered already in the 1830s, it is only in recent years that its crucial role for human health and general well-being has been increasingly realized and appreciated. A number of beneficial health effects have been ascribed to oral creatine supplementation, such as neuroprotective, ergogenic, anti-diabetic, anti-inflammatory, antiviral, or antitumor effects. Creatine may even improve memory and intelligence. In the present book, emphasis is placed on the intricate interplay between creatine and creatine kinase function on one hand, and proper brain function, neurodegenerative disease and/or neuroprotection on the other hand.The book also elaborates on the recently identified inborn errors of creatine biosynthesis and transport, the so-called cerebral creatine deficiency syndromes. The clinical hallmarks of these disorders are mental retardation, epilepsy, autistic-like behaviour, and speech and language delay. In addition, the muscle growth- and strength-promoting effects, the pharmacokinetics and the safety of oral creatine supplementation are discussed. Finally, the present book outlines the emerging "systems biology" approaches for understanding the ...

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