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Complex enzymes in microbial natural product biosynthesis, Part B: polyketides, aminocoumarins and carbohydrates

Description: Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results. Moreover understanding the biosynthesis of complex natural products was frustratingly difficult. With the development of molecular genetic methods to isolate and manipulate the complex microbial enzymes that make natural products, unexpected chemistry has been revealed and interest in the compounds has again flowered. This two-volume treatment of the subject will showcase the most important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. In both classes, variation in sub-unit structure, number and chemical modification leads to an almost infinite variety of final structures, accounting for the huge importance of the compounds in nature and medicine.

* Gathers tried and tested methods and techniques from top players in the field.

* Provides an extremely useful reference for the experienced research scientist.

* Covers biosynthesis of Polyketides, Tarpenoids, Aminocoumarins and Crabohydrates

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	Science/Engineering Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids Biosynthesis: Aromatic Polyketides, Isoprenoids, AlkaloidsSpringer \| ISBN:3540665730 \| Edition - April 26, 2000 \| PDF \| 247 pages \| 3 MBThis book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of ...
	Science/Engineering Complex enzymes in microbial natural product biosynthesis, Part A: overview articles and peptides (2009) Complex enzymes in microbial natural product biosynthesis, Part A: overview articles and peptidesPublisher: Academic Press \| Language: English \| ISBN:0123745888 \| 350 pages \| Data: 2009 \| PDF \| 8 MbDescription: Microbial natural products h ...
	Science/Engineering Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids (Topics in Current Chemistry) by Finian J. Leeper Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids (Topics in Current Chemistry) by Finian J. LeeperPublisher: Springer \| April 26, 2000 \| ISBN: 3540665730 \| Pages: 247 \| PDF \| 3.4 MBThis book is the second of two volumes that deal ...
	Study Complex Sciences: First International Conference, Complex 2009, Part 2 Jie Zhou, "Complex Sciences: First International Conference, Complex 2009, Part 2" Springer \| 2009 \| ISBN: 3642024688 \| 1236 pages \| PDF \| 39,7 MB This book constitutes the thoroughly refereed post-conference proceedings of the First Inte ...
	Science/Engineering Complex Sciences: First International Conference, Complex 2009, Shanghai, China, February 23-25, 2009. Complex Sciences: First International Conference, Complex 2009, Shanghai, China, February 23-25, 2009. Revised Selected Papers (Lecture Notes of the Institute ... and Telecommunications Engineering) English \| Springer \| 2009-08-01 \| 1189 p ...
	Family & Home Complex Carbohydrates in Foods (Food Science and Technology, 93): Sungsoo Cho, Leon Prosky, Mark L. Dreher Complex Carbohydrates in Foods (Food Science and Technology, 93): Sungsoo Cho, Leon Prosky, Mark L. Dreher CRC \| ISBN: 0824701879 \| 1999-01-19 \| PDF (OCR) \| 700 pages \| 2.51 Mb "Explores the effects of complex carbohydrates (starch, gums, ...

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	Science/Engineering Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids Biosynthesis: Aromatic Polyketides, Isoprenoids, AlkaloidsSpringer \| ISBN:3540665730 \| Edition - April 26, 2000 \| PDF \| 247 pages \| 3 MBThis book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of ...
	Science/Engineering Complex enzymes in microbial natural product biosynthesis, Part A: overview articles and peptides (2009) Complex enzymes in microbial natural product biosynthesis, Part A: overview articles and peptidesPublisher: Academic Press \| Language: English \| ISBN:0123745888 \| 350 pages \| Data: 2009 \| PDF \| 8 MbDescription: Microbial natural products h ...
	Science/Engineering Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids (Topics in Current Chemistry) by Finian J. Leeper Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids (Topics in Current Chemistry) by Finian J. LeeperPublisher: Springer \| April 26, 2000 \| ISBN: 3540665730 \| Pages: 247 \| PDF \| 3.4 MBThis book is the second of two volumes that deal ...
	Study Complex Sciences: First International Conference, Complex 2009, Part 2 Jie Zhou, "Complex Sciences: First International Conference, Complex 2009, Part 2" Springer \| 2009 \| ISBN: 3642024688 \| 1236 pages \| PDF \| 39,7 MB This book constitutes the thoroughly refereed post-conference proceedings of the First Inte ...
	Science/Engineering Complex Sciences: First International Conference, Complex 2009, Shanghai, China, February 23-25, 2009. Complex Sciences: First International Conference, Complex 2009, Shanghai, China, February 23-25, 2009. Revised Selected Papers (Lecture Notes of the Institute ... and Telecommunications Engineering) English \| Springer \| 2009-08-01 \| 1189 p ...
	Family & Home Complex Carbohydrates in Foods (Food Science and Technology, 93): Sungsoo Cho, Leon Prosky, Mark L. Dreher Complex Carbohydrates in Foods (Food Science and Technology, 93): Sungsoo Cho, Leon Prosky, Mark L. Dreher CRC \| ISBN: 0824701879 \| 1999-01-19 \| PDF (OCR) \| 700 pages \| 2.51 Mb "Explores the effects of complex carbohydrates (starch, gums, ...

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