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Complement Regulatory Proteins

From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book does just that. The first few chapters discuss the "nuts-and-bolts" of the complement regulators, describing their structures, functional roles and modes of action. The roles of the complement regulators in vivo are then described, focusing on the consequences of deficiency, roles in the reproductive system, interactions with pathogens and exploitation for therapy. The interesting developments in defining the complement regulators expressed in other species are also discussed. The book is written as a monograph, albeit by two people. The text is as readable as possible without compromising on scientific accuracy and completeness. The conversational style very evident in some sections is deliberate! Placing all references in a single bibliography at the end of the text further improves readability. The reader will go to the book to discover a specific fact but be persuaded to read more and derive pleasure from the process. The authors' enthusiasm for the subject comes over strongly in the text, and this enthusiasm proves infectious.

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	Business/Investing Securities Regulatory Handbook: 2001-2002 (Pricewaterhousecoopers Regulatory Handbooks) PricewaterhouseCoopers, "Securities Regulatory Handbook: 2001-2002 (Pricewaterhousecoopers Regulatory Handbooks)"Publisher: M.E. Sharpe \| 2001 \| ISBN 0765606542 \| PDF \| 144 pages \| 4.6 MBA guide, for financial institutions, to constraints o ...
	Economics/Finances The Consumer Banking Regulatory Handbook: 2001-2002 (Pricewaterhousecoopers Regulatory Handbooks) PricewaterhouseCoopers, "The Consumer Banking Regulatory Handbook: 2001-2002 (Pricewaterhousecoopers Regulatory Handbooks)"Publisher: M.E. Sharpe \| 2001 \| ISBN 0765606526 \| PDF \| 248 pages \| 14.54 MBThis work was compiled with the aim of ke ...
	Science/Engineering The Schur Complement and Its Applications The Schur Complement and Its Applications (Numerical Methods and Algorithms) Springer \| 2005 \| ISBN: 0387242716 \| 296 pages \| PDF \| 10,3 MB The Schur complement plays an important role in matrix analysis, statistics, numerical analysis, ...
	Science/Engineering Handbook of Biogeneric Therapeutic Proteins: Regulatory, Manufacturing, Testing, and Patent Issues Handbook of Biogeneric Therapeutic Proteins: Regulatory, Manufacturing, Testing, and Patent Issues By Sarfaraz K. Niazi Publisher: Informa Healthcare \| ISBN: 0849329914 \| edition 2005 \| PDF \| 584 pages \| 4,2 mb Handbook of Biogeneric The ...
	Science/Engineering The Regulatory Genome: Gene Regulatory Networks In Development And Evolution Eric H. Davidson, "The Regulatory Genome: Gene Regulatory Networks In Development And Evolution"Academic Press \| 2006-05-30 \| ISBN: 0120885638 \| 304 pages \| PDF \| 5,7 MBGene regulatory networks are the most complex, extensive control sy ...
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