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Science/Engineering Clinical Trials: A Methodologic Perspective

Posted on 2010-04-12




Name:Science/Engineering Clinical Trials: A Methodologic Perspective
ASIN/ISBN:0471163937
Language:English
File size:1.9 Mb
Publish Date: 1997-04-07
File Size: 1.9 MB
Other Info: Wiley-Interscience; 0471163937; 624 p; html
   Science/Engineering Clinical Trials: A Methodologic Perspective

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More Steven Piantadosi, "Clinical Trials: A Methodologic Perspective"

This book gives the reader important accounts of basic statistical procedures used in clinical trials. It covers several areas of study, including biostatics, biomathematics, biometry and epidemiology. There is emphasis for trialists to learn good methodology while giving quality clinical treatment. Discusses and explores controversial issues such as ethics and offers pragmatic information regarding allegations of fraud or misconduct.

Summary: unusually well-written text on the statistical aspects

Rating: 5

This book is very unique. Basic statistical concepts are clearly presented but only those concepts that are important in clinical trials. The author presents all the issues with clinical trials including ethical issues with some historical perspective. Principles of randomization and statistical design are clearly presented. It offers discussion of Bayesian techniques and meta-analyses, cross-over designs and group sequential methods (interim analyses). For statisticians doing clinical research like myself, this is a valuable reference source.

Summary: Clinical Trials: A Methodologic Perspective Second Edition

Rating: 5

This is an excellent book. It outlines the important issues of clinical trials well. It is understandable and thorough. A must for anyone who is interested in actually doing trials. Not a good book for a brief, superficial overview.

Summary: presents clinical trials issues and methodology clearly

Rating: 5

This book is very unique. Basic statistical concepts are clearly presented but only those concepts that are important in clinical trials. The author presents all the issues with clinical trials including ethical issues with some historical perspective. Principles of randomization and statistical design are clearly presented. It offers discussion of Bayesian techniques and meta-analyses, cross-over designs and group sequential methods (interim analyses). For statisticians doing clinical research like myself, this is a valuable reference source.

Summary: The best start in clinical trial

Rating: 5

The amount of knowledge and the scope of this book are the exact need for the first contact with clinical trials. Yet, it is not a simple or superficial text. Instead, it not only will guide the reader through the basics of trials (and there is so much that is not basic in it) but the author points the reader to hundreds of papers and books that are landmarks. I regard this book itself as one of these landmarks!

Summary: Most up-to-date and thorough cover of Clinical Trials

Rating: 5

Covers many aspects of trials (particularly facets of design and analysis)not yet covered by other books, eg randomisation with minimisation, and meta-analysis of trial results. Readable, applicable, practical, good references, well structured.

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