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Chemistry and Biology of Hyaluronan by Hari G. Garg
Posted on 2010-06-08
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More A hyaluronan molecule is generally of high molecular weight and occupies through its random-coil configuration a large hydrodynamic volume in solution. At higher concentrations, hyaluronan molecules entangle and form continuous networks. Such solutions are endowed with interesting rheological properties. They are visco-elastic and the viscosity is strongly shear-dependent. For this reason, hyaluronan can act as a lubricant. It is found in joints and other tissues such as muscles at surfaces which are moving over each other. The human body is a well-oiled machine and hyaluronan seems to be that oil.
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