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Science/Engineering Checkpoint Controls and Cancer: Volume 2: Activation and Regulation Protocols by Axel H. Schönthal

Posted on 2010-03-16




Name:Science/Engineering Checkpoint Controls and Cancer: Volume 2: Activation and Regulation Protocols by Axel H. Schönthal
ASIN/ISBN:1588295001
Language:English
File size:3.85 Mb
Publisher: Humana Press
Publish Date: June 24, 2004
ISBN: 1588295001
Pages: 348
File Type: PDF
File Size: 3.85 MB
   Science/Engineering Checkpoint Controls and Cancer: Volume 2: Activation and Regulation Protocols by Axel H. Schönthal



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Checkpoint Controls and Cancer: Volume 2: Activation and Regulation Protocols

(Methods in Molecular Biology) by Axel H. Schönthal


Prestigious researchers from ten different countries present readily reproducible experimental protocols to study the molecular components of checkpoint controls and their regulation. Described in step-by-step detail, these cutting-edge techniques offer novel approaches, such as the use of genome databases and siRNA, to analyzing how cells of the human body can escape proper surveillance to grow into a tumor. Additional experimental methods are provided for the manipulation of checkpoint pathways and the analysis of the resulting consequences for the cellular phenotype. An earlier first volume, Reviews and Model Systems, comprehensively reviews the complexities of checkpoint controls and the model systems needed to study them.

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