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Science/Engineering Statistical Mechanics, Third Edition
Science/Engineering Essentials of Toxic Chemical Risk: Science and Society
Science/Engineering Telefoncoaching: So machen Sie aus Ihren Mitarbeitern Telefonprofis
Science/Engineering Wireless Communications (Wiley - IEEE)
Science/Engineering Posttraumatische Belastungsstörungen (German Edition)
Science/Engineering Lernplattformen in Schulen: Ansätze für E-Learning und Blended Learning in Präsenzklassen (1 Auflage)
Science/Engineering Stochastik für Einsteiger: Eine Einführung in die faszinierende Welt des Zufalls. Mit über 220 Übungsaufgaben und Lösungen {Repost}
Science/Engineering Testtheorie und Fragebogenkonstruktion (Springer-Lehrbuch)
Science/Engineering Centrifugal Pumps, 2nd Edition
Science/Engineering Computational Intelligence for Modelling and Prediction (Studies in Computational Intelligence) 1 edition {Repost}
Science/Engineering Networks, Crowds, and Markets: Reasoning About a Highly Connected World {repost}
Science/Engineering Introduction to Biophotonics (repost)
Science/Engineering The Art and Science of Psychotherapy (repost)
Science/Engineering Advances in Chemical Physics - Volume 15: Stochastic Processes in Chemical Physics
Science/Engineering "Emulsion Science: Basic Principles" (repost)
Science/Engineering Elementary Principles of Chemical Processes 3rd edition
Science/Engineering Boundary Element Analysis (repost)
Science/Engineering Collection of books on physics 2
Science/Engineering A Practical Handbook of Preparative HPLC by Donald A. Wellings (Repost)
Science/Engineering Reviews of Environmental Contamination and Toxicology 184 by George W. Ware
Science/Engineering Essentials of Toxic Chemical Risk: Science and Society
Science/Engineering Telefoncoaching: So machen Sie aus Ihren Mitarbeitern Telefonprofis
Science/Engineering Wireless Communications (Wiley - IEEE)
Science/Engineering Posttraumatische Belastungsstörungen (German Edition)
Science/Engineering Lernplattformen in Schulen: Ansätze für E-Learning und Blended Learning in Präsenzklassen (1 Auflage)
Science/Engineering Stochastik für Einsteiger: Eine Einführung in die faszinierende Welt des Zufalls. Mit über 220 Übungsaufgaben und Lösungen {Repost}
Science/Engineering Testtheorie und Fragebogenkonstruktion (Springer-Lehrbuch)
Science/Engineering Centrifugal Pumps, 2nd Edition
Science/Engineering Computational Intelligence for Modelling and Prediction (Studies in Computational Intelligence) 1 edition {Repost}
Science/Engineering Networks, Crowds, and Markets: Reasoning About a Highly Connected World {repost}
Science/Engineering Introduction to Biophotonics (repost)
Science/Engineering The Art and Science of Psychotherapy (repost)
Science/Engineering Advances in Chemical Physics - Volume 15: Stochastic Processes in Chemical Physics
Science/Engineering "Emulsion Science: Basic Principles" (repost)
Science/Engineering Elementary Principles of Chemical Processes 3rd edition
Science/Engineering Boundary Element Analysis (repost)
Science/Engineering Collection of books on physics 2
Science/Engineering A Practical Handbook of Preparative HPLC by Donald A. Wellings (Repost)
Science/Engineering Reviews of Environmental Contamination and Toxicology 184 by George W. Ware
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Science/Engineering Cell Colonization Control by Physical and Chemical Modification of Materials
Posted on 2010-03-16
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More L. Baeakova, V. Ivoreik, "Cell Colonization Control by Physical and Chemical Modification of Materials" Cell-material interface plays a key role in the interaction of cells with artificial materials designed for construction of body implants or tissue engineering. Physical and chemical properties of the material surface, such as its polarity, wettability, electrical charge and conductivity, roughness and morphology, rigidity or elasticity as well as the presence of various chemical functional groups, strongly influence the cell adhesion. The latter is mediated by adsorption of cell adhesion-mediating molecules (eg: vitronectin, fibronectin, collagen, laminin, fibrinogen) from the serum of the culture medium or body fluids in appropriate spatial conformation or flexibility enabling the accessibility of specific sites on these molecules (eg: certain amino acid sequences or saccharide-based ligands) by adhesion receptors on the cell membrane (eg: integrins).After binding these ligands, the adhesion receptors are recruited into focal adhesion plaques, where they associate with cascades of various structural and signalling molecules, such as cytoskeletal proteins and kinases. By these cascades, the signal provided by the cell-material interaction is delivered to the cell nucleus. It influences the gene expression, and thus the further behavior of cells, manifested by their viability, synthesis of various molecules, proliferation, differentiation, functioning, immune activation, stress adaptation or cell death.This interdisciplinary review involves: physical modifications of the material surface by plasma discharge, irradiation with ions or ultraviolet light and effects of these modifications on the surface wettability, electrical conductivity and formation of chemical functional groups influencing cell adhesion; deposition of organic or inorganic layers on the material surfaces, especially those nanostructured (eg: nanofibers of fibrin and extracellular matrix molecules, carbon nanoparticles, such as nanodiamonds, fullerenes and nanotubes, nanocomposite metal/C:H layers); functionalisation of the material surface with amino acids and oligopeptidic ligands for cell adhesion receptors (e.g., GRGDSG); and, effect of all these modifications on the extent and strength of adhesion of vascular and bone-derived cells, cell proliferation activity, switch between cell proliferation and differentiation, expression of cell-type specific markers of differentiation and other cell functions. Enjoy this great book! Brought to you by SMIRK
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