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Science/Engineering Cancer Epigenetics

Posted on 2010-03-15




Name:Science/Engineering Cancer Epigenetics
ASIN/ISBN:1420045792
Language:English
File size:4.2 Mb
Publish Date: 2008-09-19
ISBN: 1420045792
Pages: 472 pages
File Type: PDF
File Size: 4,2 MB
Other Info: CRC
   Science/Engineering Cancer Epigenetics

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Trygve Tollefsbol "Cancer Epigenetics"

During the past few decades, it has become increasingly apparent that heredity is not the sole determining factor in disease development, such as cancer. This landmark work covers a wide array of aspects in the relatively new area of epigenetics, ranging from its role in the basic mechanisms of tumorigenesis, to the newest epigenetic drugs being developed and used for cancer therapy.

Cancer Epigenetics presents in-depth discussions of DNA methylation alterations, histone and RNA modifications, and nucleosome remodeling, which are all intimately involved in the formation of tumors. It also analyzes metabolic influences on cancer epigenetics and advances in epigenetic cancer gene therapy.

Discusses the Latest Advances in the Role of Epigenetics in Tumor Initiation, Progression, and Metastasis

With stand-alone chapters written by research pioneers in the field, this definitive resource covers

DNA methylation and cancer Histone modifications in cancer Emerging areas of cancer epigenetics Epigenetics in the diagnosis, prognosis, and therapy of cancer Future directions in epigenetic cancer research

Bringing together different topics into a single compilation, this text is a prime resource for those with interests ranging from the basic mechanisms of tumor biology to cancer therapy. It also serves as a core textbook for advanced courses with a focus on genetic diseases, molecular biology, and/or cancer. This seminal work answers the call for a thorough and authoritative reference that covers the critical and contemporary aspects of this revolutionary field.

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