Science/Engineering Brain Barrier Systems by Abel Lajtha (0444403523)

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Brain Barrier Systems by Abel Lajtha

In recent years, many important developments have occurred in many research disciplines that are directly related to brain permeability. In morphological fields, the fine resolution provided by electron microscopy has resulted in new concepts of membrane structure. Electron microscopy, combined with autoradiography, have contributed significant information concerning dynamic events occurring in and around such membranes. Permeability measurements with drugs have led to new Theories of the physical and chemical requirements which determine the penetration of drugs into the central nervous system. Measurements of permeability during development and in later more mature stages of life have resulted in theories that relate brain permeability and function and, as in senescence, brain permeability and pathology. Recent work with normal metabolites in the brain has shown complex active transport mechanisms to be present in the walls of the various cell types making up the nervous system. Cerebral transport phenomena have been shown to have a considerable degree of selectivity and specificity and seem highly significant in controlling the mechanisms of brain metabolism. Inasmuch as these membranes and transport systems sometimes appear to restrict entry of materials into the brain, it is apparent that they represent, in part at least, what has been termed the “Blood-Brain Barrier”

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	Business Leading Strategic Change: Breaking Through the Brain Barrier by J. Stewart Black Leading Strategic Change: Breaking Through the Brain Barrier by J. Stewart Black (Author), Hal B. Gregersen (Author)Publisher: FT Press; 1st edition (June 23, 2003) \| ISBN-10: 0131303198 \| PDF \| 4,6 Mb \| 224 pagesStephen R. Covey, author o ...
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	Science/Engineering Leading Strategic Change: Breaking Through the Brain Barrier by: J. Stewart Black Hal B. Gregersen Leading Strategic Change: Breaking Through the Brain Barrier by: J. Stewart Black Hal B. GregersenPublisher: Financial Times/ Prentice Hall \| 4 Mar 2004 \| ISBN: 0131303198 \| Pages: 224 \| PDF \| 9.37 MBOf organizations that seek strategic cha ...
	The Blood-Brain Barrier and Its Microenvironment The Blood-Brain Barrier and Its Microenvironment: Basic Physiology to Neurological Disease Publisher:Informa HealthCare \| Pages:544 \| 2005-08-24 \| ISBN:0849398924 \| PDF \| 3.7 MBThis reference analyzes the cellular and molecular biology and ...
	The Blood-Brain Barrier and Drug Delivery to the CNS Veterinary Human Toxicology, 2000"Several exciting areas of research are spotlighted...an invaluable resource." Review" ...a compact monograph that brings readers up to date on the blood-brain barrier and how scientists determine drug/chemi ...
	Leading Strategic Change: Breaking Through the Brain Barrier Author: Hal B. Gregersen, J. Stewart BlackPublisher: FT Press (2003)Binding: Paperback, 224 pagespricer: $16.99ISBN-10: 0131303198editorialreviewsOf organizations that seek strategic change, 70% fail. In Leading Strategic Change,now in pape ...

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