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Science/Engineering Assessing Bioavailablility of Drug Delivery Systems: Mathematical Modeling

Posted on 2010-03-16




Name:Science/Engineering Assessing Bioavailablility of Drug Delivery Systems: Mathematical Modeling
ASIN/ISBN:0849330440
Language:English
File size:7 Mb
Publisher: CRC; 1 edition
Publish Date: 2005-05-26
Pages: 227 Pages
ISBN: 0849330440
File Type: PDF
File Size: 7 MB
   Science/Engineering Assessing Bioavailablility of Drug Delivery Systems: Mathematical Modeling

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Jean-Maurice Vergnaud, Iosif-Daniel Rosca, "Assessing Bioavailablility of Drug Delivery Systems: Mathematical Modeling"

This book introduces mathematical modeling methods for calculating the profiles of plasma levels obtained with controlled release dosage forms and provides examples and case studies to illustrate the techniques employed. The mathematical models developed by the author are particularly powerful because they account for such major parameters as the kinetics of drug release controlled by diffusion or by erosion, and the kinetics of absorption into and elimination out of the plasma. They are also able to solve the problem of determining the drug level in plasma as a result of patient non-compliance, incorrect dosage, and incorrect frequency, and to determine the best dosage forms necessary for therapy.

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