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Technical Antigenic Variation

Posted on 2010-04-14




Name:Technical Antigenic Variation
ASIN/ISBN:012194851X
Publish Date:012194851X
Language:English
Pages:464 pages
File size:6.63 Mb
Language: English
Publish Date: 012194851X
Pages: 464 pages
File Type: PDF
File Size: 6.63 MB
Other Info: Academic Press; 1 edition (October 8, 2003)
   Technical Antigenic Variation

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Alister G. Craig, Artur Scherf, "Antigenic Variation"

An entire book devoted to antigenic variation, which is a major way by which microbes evade the immune response and persist in the body.

The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent.

The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites - one of the most fascinating groups of organisms exhibiting this behaviour.

- Comprehensive coverage of antigenic variation from viruses to parasites

- Discussions devoted to molecular mechanisms of host evasion

- Detailed descriptions of host/pathogen interactions

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