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Medical Anticancer Agents from Natural Products

Posted on 2010-03-15




Name:Medical Anticancer Agents from Natural Products
ASIN/ISBN:0849318637
Language:English
File size:25.5 Mb
Pages: 600 Pages
Other Info: Hardcover; List Price: $179.95 (USD); Sales Rank: 291456
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Title: Anticancer Agents from Natural Products 2005-06

Author: Gordon M. Cragg (Editor), David J. Newman (Editor), David G. Kingston (Editor), David G.I. Kingston (Editor)

Publisher: CRC

Publication Date: 2005-06-13

Number Of Pages: 600

Anticancer Agents from Natural Products

By: Gordon M. Cragg(Editor) David G. I. Kingston(Editor) David J. Newman(Editor)

ISBN: 0849318637

Publisher: CRC - 2005-06-13

Anticancer Agents from Natural Products

By: Gordon M. Cragg(Editor) David G. I. Kingston(Editor) David J. Newman(Editor)

ISBN: 0849318637

Publisher: CRC - 2005-06-13

Table of Contents

Ch. 1 Introduction 1

Ch. 2 Champtothecin and its analogs 5

Ch. 3 The discovery and development of the combretastatins 23

Ch. 4 Homoharringtonine and related compounds 47

Ch. 5 Podophyllotoxins and analogs 71

Ch. 6 Taxol and its analogs 89

Ch. 7 The vinca alkaloids 123

Ch. 8 The bryostatins 137

Ch. 9 The isolation, characterization, and development of a novel class of potent antimitotic macrocyclic depsipeptides : the cryptophycins 151

Ch. 10 Chemistry and biology of the discodermolides, potent mitotic spindle poisons 171

Ch. 11 The dolastatins : novel antitumor agents from Dolabella auricularia 191

Ch. 12 Ecteinascidin 743 (ET-743; Yondelis), aplidin, and kahalaide F 215

Ch. 13 Discovery of E7389, a fully synthetic macrocyclic ketone analog of halichondrin B 241

Ch. 14 HTI-286, a synthetic analog of the antimitotic natural product hemiasterlin 267

Ch. 15 The actinomycins 281

Ch. 16 Anthracyclines 299

Ch. 17 Ansamitocins (maytansinoids) 321

Ch. 18 Benzoquinone ansamycins 339

Ch. 19 Bleomycin group antitumor agents 357

Ch. 20 Biochemical and biological evaluation of (+)-CC-1065 analogs and conjugates with polyamides 383

Ch. 21 Epothilone, a myxobacterial metabolite with promising antitumor activity 413

Ch. 22 Enediynes 451

Ch. 23 The mitomycins 475

Ch. 24 Staurosporines and structurally related indolocarbazoles as antitumor agents 499

Ch. 25 Combinatorial biosynthesis of anticancer natural products 519

Ch. 26 Developments and future trends in anticancer natural products drug discovery 553

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