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Newest
Encyclopedias The Subtle Body: An Encyclopedia of Your Energetic Anatomy
Encyclopedias Encyclopedia of Microfluidics and Nanofluidics [Repost]
Encyclopedias Encyclopedia of Complexity and Systems Science [Repost]
Encyclopedias The Encyclopedia of Applied Animal Behaviour and Welfare
Encyclopedias Space - A Visual Encyclopedia
Encyclopedias Encyclopedia of Knowledge Management, Second Edition
Encyclopedias Encyclopedia of India (4 Volume Set) [Repost]
Encyclopedias The MMA Encyclopedia (repost)
Encyclopedias Skew Fields - Theory of General Division Rings (Encyclopedia of Mathematics and its Applications) by P. M. Cohn
Encyclopedias Books and Beyond - The Greenwood Encyclopedia of New American Reading
Encyclopedias The Gale Encyclopedia of Genetic Disorders (3rd edition)
Encyclopedias Encyclopedia of African American Popular Culture, 4 Volume Set (repost)
Encyclopedias The American Economy: A Historical Encyclopedia (2 volume set) [Repost]
Encyclopedias Encyclopedia of the Black Death
Encyclopedias Encyclopedia of Grain Science (repost)
Encyclopedias Ashfaq A. Marghoob, "An Atlas of Dermoscopy (Encyclopedia of Visual Medicine Series)"
Encyclopedias Jordan Goodman, "Tobacco in History and Culture: An Encyclopedia" (2 Volume set)
Encyclopedias The Encyclopedia of Operations Management - A Field Manual and Glossary of Operations Management Terms and Concepts
Encyclopedias UXL Encyclopedia of Diseases and Disorders: Volume 5
Encyclopedias Encyclopedia Gothica
Encyclopedias Encyclopedia of Microfluidics and Nanofluidics [Repost]
Encyclopedias Encyclopedia of Complexity and Systems Science [Repost]
Encyclopedias The Encyclopedia of Applied Animal Behaviour and Welfare
Encyclopedias Space - A Visual Encyclopedia
Encyclopedias Encyclopedia of Knowledge Management, Second Edition
Encyclopedias Encyclopedia of India (4 Volume Set) [Repost]
Encyclopedias The MMA Encyclopedia (repost)
Encyclopedias Skew Fields - Theory of General Division Rings (Encyclopedia of Mathematics and its Applications) by P. M. Cohn
Encyclopedias Books and Beyond - The Greenwood Encyclopedia of New American Reading
Encyclopedias The Gale Encyclopedia of Genetic Disorders (3rd edition)
Encyclopedias Encyclopedia of African American Popular Culture, 4 Volume Set (repost)
Encyclopedias The American Economy: A Historical Encyclopedia (2 volume set) [Repost]
Encyclopedias Encyclopedia of the Black Death
Encyclopedias Encyclopedia of Grain Science (repost)
Encyclopedias Ashfaq A. Marghoob, "An Atlas of Dermoscopy (Encyclopedia of Visual Medicine Series)"
Encyclopedias Jordan Goodman, "Tobacco in History and Culture: An Encyclopedia" (2 Volume set)
Encyclopedias The Encyclopedia of Operations Management - A Field Manual and Glossary of Operations Management Terms and Concepts
Encyclopedias UXL Encyclopedia of Diseases and Disorders: Volume 5
Encyclopedias Encyclopedia Gothica
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Encyclopedias Aging of the Genome - The Dual Role of DNA in Life and Death - J. Vijg (Repost)
Posted on 2010-06-04
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More Aging of the Genome - The Dual Role of DNA in Life and Death - J. Vijg Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleterious effects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases. Moreover, there is a growing public recognition of the imperative of understanding more about the underlying biology of aging, driven by continuing demographic change.
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