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Advanced Genetic Analysis: Finding Meaning in a Genome

Posted on 2010-03-16




Name:Advanced Genetic Analysis: Finding Meaning in a Genome
ASIN/ISBN:1405103361
Language:English
File size:85.1 Mb
Publish Date: 2003
ISBN: 1405103361, 1405123923
Pages: 256 pages
File Type: PDF
File Size: 85,1 MB
Other Info: Wiley-Blackwell
   Advanced Genetic Analysis: Finding Meaning in a Genome

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R. Scott Hawley, Michelle Y. Walker, ""

Stowers Institute for Medical Research. Textbook providing essential analytic tools covering gene mutation and function to gene mapping and chromosome segregation. Abundant illustrations are used to illustrate difficult genetic concepts. Suitable for advanced courses in genetic analysis.

Summary: Outstanding text

Rating: 5

This is an outstanding textbook for a course in (surprise) Advanced Genetic Analysis. As previous reviewers have indicated, it is a book any practicing geneticist should love. It describes the logic, and well as the methodology of genetic analysis, and provides brief descriptions of various model organisms (including Arabidopsis!). Furthermore, the writing is beautiful--Hawley and Walker should be complemented for producing a genetics textbook that is both entertaining to read as well as informative. My only complaint is that it is too brief and a little uneven. Some topics are missing or are dealt with in only a few sentences (e.g. positional cloning/molecular markers, genetic analysis of natural variation, mapping tools such as RILs) and others (meiotic recombination--the author's specialty) receive a bit too much emphasis. Hopefully, these minor flaws will be corrected in a new edition. I wish I had stumbled across this text when it first came out. It would have saved me a lot of photocopying.

Summary: Excellent text for grad level genetics

Rating: 5

This is an excellent, concise text for classical genetics. While most introductory texts like "Introduction to Genetic Analysis" is 90% molecular biology and 10% genetics, this book assumes that the reader has enough background to skip the usual obligatory exposition on DNA and translation, etc., and jumps straight to topics such as designing mutagenesis screens and epistatic analysis. This book is particularly strong in presenting genetics formalism to new students, and concepts usually glossed over in other texts (eg. dominant/recessive alleles, complementation) are explained in great detail, and possible pitfalls in experiment or interpretation are frequently discussed.

Researchers and students working on specific model organisms may find this book a little too general, but it is the perfect text for new grad students interested in genetics.

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