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Science/Engineering Vaccinia Virus and Poxvirology: Methods and Protocols (Methods in Molecular Biology) (Methods in Molecular Biology)
Posted on 2010-04-28
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Publisher: Humana Press (2004) Binding: Hardcover, 416 pages pricer: $164.50 ISBN-10: 1588292290 editorialreviews A comprehensive collection of cutting-edge methods to study and work with the vaccinia virus and other poxvirus gene transcriptions. These readily reproducible techniques can be used for the construction and characterization of recombinant viruses; for the study of poxvirus gene transcription and DNA replication; for the investigation of the binding, entry, and movement of the virus in host cells; and for the use of the virus in immunologic and cell-cell fusion assays. Other methods cover poxvirus bioinformatics, aspects of viral pathogenesis at both a protein and an animal model level, and the study of immune responses to poxviruses-the latter a critical ability given the important role of vaccinia virus in smallpox vaccination and their potential role as vaccine vectors directed against infectious agents and cancer. checked
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