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Science/Engineering Regulation of Gene Expression: Molecular Mechanisms

Posted on 2010-04-10




Name:Science/Engineering Regulation of Gene Expression: Molecular Mechanisms
ASIN/ISBN:1588292657
Language:English
File size:2.88 Mb
Publish Date: Edition - 2006
File Type: PDF
Pages: 333 pages
File Size: 2.88 MB
Other Info: Humana Press; 1588292657; Rapidshare & Megaupload
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Regulation of Gene Expression: Molecular Mechanisms

Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms that may result in altered activity of a specific cell protein.

Each of three sections explores mechanisms of gene regulation and expression, and presents methods and protocols for achieving specific experimental goals. Part I focuses on approaches for studying control of mRNA expression and determining target genes for a given transcription copy. Part II outlines the methods for determining how proteins can regulate each other by mediating synthesis, degradation, protein-protein interactions, and posttranslational modification. Part III explores how gene targeting techniques in mice can provide insight into protein function. This volume provides a clear, concise overview of the protocols and techniques used to examine chemically or disease-mediated alterations in gene expression in mammalian systems.

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